Tuesday, April 30, 2024

Iron Plays a Certain Role in Patterned Hair Loss PMC

does iron deficiency cause hair loss

Folate is a coenzyme in the synthesis of nucleic acids and in amino acid metabolism. It exists in the plasma as 5-methyl-tetrahydrofolate, while about half of the total body content exists in the liver [22, 41]. The recommended dietary allowance of food folate is 400 mcg daily for adults, which is supported by required fortification of some foods in the USA [22]. While most people in the USA ingest adequate amounts of folate, certain groups are at risk for deficiency (usually in association with poor diet, alcoholism, or a malabsorptive disorder).

How to add more iron to your diet

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P values less than 0.05 were considered as a statistical significance. To compare patients with normal healthy controls, Student t-test was conducted. Regression analysis was done to see relation between age and other parameters.

If iron deficiency anaemia is not treated

Exogenous biotin in the sample competes with biotinylated reagents for the binding sites on streptavidin reagents, creating false positive or false negative results [29]. Other non-hormonal tests include cardiac and tumor markers, infectious disease serologies, biomarkers of anemia and autoimmune diseases, and concentrations of immunosuppressive drugs [29–32]. Consumption of vitamin A exceeding the recommended daily limit of approximately 10,000 IU a day can lead to vitamin A toxicity. In a case report, a 60-year-old male who had been taking excess vitamin A supplements experienced non-scarring fronto-central alopecia as well as decreased pubic and axillary hair. The patient also reported dystrophic nail changes and an erythematous rash. Taken together, these changes were concurrent with drug toxicity that aligned with the patient’s over-consumption of vitamin A [21].

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A rare condition called iron-refractory iron deficiency anemia is a form of anemia that you can inherit from your parents. Babies with this condition are born with a gene mutation that causes low iron. Any injury that causes you to lose blood can cause iron deficiency anemia. Iron deficiency anemia is when your body doesn’t have enough red blood cells.

In ID and anemia, supplementation is required, but patients with ID in the absence of anemia must be approached on a case-by-case basis. Some authors believe that raising levels of storage iron may improve hair loss, although the research is not conclusive. All patients receiving iron supplementation must be monitored due to toxicity risk.

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Research has determined that there is not enough evidence to say for sure that iron deficiency anemia can cause hair loss in men or women. While some studies have found that people experiencing hair loss were deficient in iron, there is little evidence to suggest that an iron deficiency is the cause. The best way to treat hair loss is to address the underlying cause of the problem. If you think your hair loss is related to an iron deficiency, consult a doctor to measure your iron levels. Your doctor will most likely order a ferritin level blood test, which measures the levels of a protein called ferritin that helps store iron.

does iron deficiency cause hair loss

Iron Deficiency Symptoms

In addition to hair loss, fatigue and cold hands and feet can be signs of both low thyroid and iron deficiency. They can be easily corrected, either with replacement thyroid hormones or iron supplements. All patients in the analysis underwent biochemical investigation at the first visit.

We consulted board-certified dermatologists Rina Weimann, MD, FAAD, and Vladyslava Doktor, MD, to find out. Keep reading for everything you need to know about the relationship between iron deficiency and hair loss. You might need to take iron supplements for a few months or more to get your levels to normal. If your intestines don't absorb iron well, you can take iron straight into your bloodstream through an intravenous tube (IV).

does iron deficiency cause hair loss

Those who had abnormal thyroid function results were also excluded from the analysis. Those currently taking iron supplements due to other cause were also excluded. People experiencing female pattern baldness may also notice a general thinning of hair on the top of your head, but hair loss typically won’t occur on the front of your scalp, per Harvard Health. According to the American Academy of Dermatology, it’s completely normal to shed anywhere between 50 to 100 strands of hair per day. However, if you’ve noticed more strands falling out of your head than normal, you may be experiencing alopecia, the medical term for hair loss. Common diagnoses include androgenetic alopecia, alopecia areata, telogen effluvium, and lymphocytic scarring alopecia, Agbai tells USA TODAY.

Anemia is common in older adults, but it can be hard to identify, as some of the symptoms are common as people get older. In people with darker skin tones, the eyelid may be the only area where this condition is noticeable. If your body doesn’t have enough hemoglobin, your tissues and muscles won’t get enough oxygen to be able to work effectively. Iron carries oxygen from your lungs to the rest of your body, giving you energy, and supporting your muscles, your brain and your immune system [1]. No one likes to see ribbon-thick sets of strands on their hairbrush or circling their shower drain, but a degree of that — particularly during or after illness — isn't uncommon. If you must use them, add a layer of protection with hair-protectant gel or mousse, which you can purchase at any supermarket or drug store.

It might have contributed to the controversy that there is no guideline to define ID. From this study, over 80% of FPHL showed serum FC lower than 70 µg/L, while only less than 20% of age matched healthy female controls showed it. No female healthy controls showed serum FC lower than 30 µg/L in this study. Therefore, serum FC lower than 30 µg/L might be a clinically significant indicator for ID especially in female hair loss patients considering their menstrual status. A retrospective cross-sectional study evaluated folate and vitamin B12 levels in 115 patients with TE (acute and chronic).

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